PEP07A NEW COOPERATION FOR DRUG DEVELOPMENT IN ONCOLOGY

BACKGROUND

We signed exclusive collaboration agreement with Sentinel Oncology in November 2020. Based on the agreement, we will co-develop PEP07, a Chk1 inhibitor, with Sentinel Oncology. The PEP07 treatment can accumulate DNA damage in cells, lead to replication catastrophe, and eventually induce cell apoptosis.

The Goals

Clinical Development
Currently we are optimizing API synthesis complying cGMP and conducting preclinical pharmacological, pharmacokinetic, and GLP toxicological studies. The development goal is to submit IND.

Indications & Stages

  • RESEARCH
  • PRECLINICAL
  • PHASE I
  • PHASE II
  • PHASE III
  • NDA

PEP07PEP07

Hematological and Solid Tumors
PRECLINICAL

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