PharmaEngine, Inc. is a biopharmaceutical company established in February 2003 with funding from TTY Biopharm and Taiwanese venture capital companies. PharmaEngine is a networked pharma company that operates according to a “Virtual Pharmaceutical Company Business Model ”model. It is led by Dr. Hong-Ren Wang and supported by a strong network of reputable advisors and consultants worldwide.
PharmaEngine focuses on the development of new drugs for the treatment of cancer diseases. There are 2 projects in the pipeline. ONIVYDE® (PEP02, MM-398, nal-IRI), a new formulation of an anti-cancer drug (irinotecan) for the patients with gemcitabine-treated metastatic pancreatic cancer, so far, ONIVYDE® has received marketing approval in more than 40 countries, including Taiwan, US, EU, Australia, Canada, South Korea, and Japan. PEP07, a checkpoint kinase 1 (Chk1) inhibitor, which targets the DNA Damage Response (DDR) network, is currently in the pre-clinical stage.
In April 2017, Ipsen S.A., a French company, completed the acquisition of ONIVYDE® from Merrimack Pharmaceuticals, Inc. for the US marketing and sales and became the new corporate partner of PharmaEngine, Inc. PharmaEngine and Ipsen are now working closely to complete NDA for worldwide approval of ONIVYDE® in the post-gemcitabine metastatic pancreatic cancer and also life cycle management of ONIVYDE® of new indications.
Meanwhile, PharmaEngine continuously puts the best efforts to move forward the clinical and pre-clinical developments of PEP07. Furthermore, PharmaEngine is actively seeking to in-license new projects for preclinical/clinical development and commercialization.